Every Trikafta assistance program you may qualify for - manufacturer and foundation programs, not a discount card. About a minute, no login.
Every Trikafta program linked to its official source, with the date we checked it - rules, income limits, and application links included.
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Trikafta (elexacaftor / tezacaftor / ivacaftor) is a cftr modulator combination made by Vertex Pharmaceuticals. It is commonly prescribed for: Cystic fibrosis with at least one F508del mutation or other responsive mutation (age >=2). Without financial assistance, Trikafta typically costs around $26,500 per month.
Income limits
1 of the 2 active Trikafta assistance programs we track caps household income. The lowest cutoff is $95,760 a year for a single person. Most programs publish their cutoff as a percent of the federal poverty level - here is what that means in dollars.
Household income at or below 600% of the federal poverty level:
| Household size | Annual income limit |
|---|---|
| 1 person | $95,760 |
| 2 people | $129,840 |
| 3 people | $163,920 |
| 4 people | $198,000 |
| Each additional person | + $34,080 |
Dollar amounts for percent-of-poverty caps are computed from the 2026 federal poverty guidelines for the 48 contiguous states and Washington, DC ($15,960 for one person, plus $5,680 for each additional household member). Alaska and Hawaii use higher figures. Each program makes the final eligibility decision - confirm on the official application linked above.
Trikafta offers more than one kind of program, and they have opposite rules:
We show both programs, and the real income limits, below. Or read the full copay card vs patient assistance guide
This is the full list before we filter by your situation. Use the calculator above to see only the ones you may qualify for.
Vertex Pharmaceuticals Inc. · Trikafta
Patient pays: as little as $0 per fill
commercial insurance
How to apply: online, phone, or fax
We couldn’t confirm the current terms - call the program to verify.
Vertex Pharmaceuticals Inc. · Trikafta
uninsured · underinsured
How to apply: online or phone
Your prescriber signs part of the form.
We couldn’t confirm the current terms - call the program to verify.
Yes. Vertex Pharmaceuticals Inc. runs the Vertex GPS Patient Assistance Program - Trikafta, which provides Trikafta free of charge to eligible patients. Household income generally needs to be at or below 600% of the federal poverty level. The full rules and the official application link are in the program list above.
Medicare coverage for Trikafta depends on your own plan: depending on how it is given, a drug can fall under Part B (administered in a clinic) or Part D (filled at a pharmacy), and each plan decides what it covers. Your plan's documents or Medicare's plan finder are the only reliable check. Separate from coverage, none of the Trikafta assistance programs we track currently accept Medicare patients.
Yes - the Vertex GPS Co-pay Assistance Program - Trikafta from Vertex Pharmaceuticals Inc. Eligible patients pay as little as $0 per fill. It works for patients with commercial (private) insurance. Patients on Medicare or Medicaid cannot use the card itself. If you searched for a Trikafta coupon, this manufacturer card is the official version of it.
Without insurance or assistance, Trikafta typically costs around $26,500 per month in the US. The Vertex GPS Patient Assistance Program - Trikafta above can bring that down substantially for eligible patients - use the calculator to check your situation.
The official application form for the Vertex GPS Patient Assistance Program - Trikafta is on vertexgps.com - the application links on this page go straight to the program's own form. Some programs call it an enrollment form; it is the same document. Applying is always free; never pay a third-party service to file a patient assistance form for you.
None of the Trikafta programs we track currently accept Medicare or Medicaid. If that changes, we will update this page.
Manufacturers like Vertex Pharmaceuticals use "patient support program" as an umbrella term for nurse lines, insurance navigation, and financial help. The financial help is what we track here - for Trikafta that is the Vertex GPS Patient Assistance Program - Trikafta. The support phone line is listed on the official program site linked above.